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Extended Live-tissue Time-Lapse Microscope

Model Information

  • Zeiss AxioObserver.Z1 inverted microscope
  • Zeiss AxioVision software



  • Fully automated Zeiss AxioObserver.Z1 inverted microscope with fluorescence and phase contrast optics
  • Marzhauser motorized z-axis stage and external filter wheels work with multiwavelengthdichroics for accurate in color registration and imaging speed for FRET
  • Cooled CCD camera with 30% quantum efficiency for high-resolution imaging


  • Extended time-lapse of tissue growth & development:
    • Iteratively monitor central 8-wells (24-well glass-bottom microtiter plate), arbitrary positions at maximum speed
    • Superb stability of software, positioning, and environmental control
    • Demonstrated 3 week continuous monitoring of murine mammary tissue and prostate tissue samples!

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